https://ogma.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Differential effects of medium- and long-chain saturated fatty acids on blood lipid profile: a systematic review and meta-analysis https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:36475 18 y. Where possible, studies were pooled for meta-analysis using RevMan 5.2. The principle summary measure was the mean difference between groups calculated using the random-effects model. Results: Eleven eligible crossover and 1 parallel trial were identified with a total of 299 participants [weighted mean ± SD age: 38 ± 3 y; weighted mean ± SD body mass index (kg/m²): 24 ± 2]. All studies were pooled for the meta-analysis. Diets enriched with MCFAs led to significantly higher high-density lipoprotein (HDL) cholesterol concentrations than diets enriched with LCSFAs (0.11 mmol/L; 95% CI: 0.07, 0.15 mmol/L) with no effect on triglyceride, low-density lipoprotein (LDL) cholesterol, and total cholesterol concentrations. Consumption of diets rich in MCFAs significantly increased apolipoprotein A-I (apoA-I) concentrations compared with diets rich in LCSFAs (0.08 g/L; 95% CI: 0.02, 0.14 g/L). There was no evidence of statistical heterogeneity for HDL cholesterol, apoA-I, and triglyceride concentrations; however, significant heterogeneity was observed for the total cholesterol (I² = 49%) and LDL cholesterol analysis (I² = 58%). Conclusion: The findings of this research demonstrate a differential effect of MCFAs and LCSFAs on HDL cholesterol concentrations. Further investigations are warranted to elucidate the mechanism by which the lipid profile is altered. This trial was registered at www.crd.york.ac.uk/PROSPERO as CRD42017078277.]]> Wed 24 Nov 2021 15:51:06 AEDT ]]> Differential effects of saturated fatty acids of varying chain length on lipid profiles in healthy individuals https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:35600 Wed 11 Sep 2019 17:41:44 AEST ]]> Prior supplementation with long chain omega-3 polyunsaturated fatty acids promotes weight loss in obese adults: a double-blinded randomised controlled trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:17007 Wed 11 Apr 2018 16:16:09 AEST ]]> Effects of dietary saturated and n-6 polyunsaturated fatty acids on the incorporation of long-chain n-3 polyunsaturated fatty acids into blood lipids https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:24376 Sat 24 Mar 2018 07:16:18 AEDT ]]> Effects of an encapsulated fruit and vegetable juice concentrate on obesity-induced systemic inflammation: a randomised controlled trial https://ogma.newcastle.edu.au/vital/access/ /manager/Repository/uon:30780 Fri 03 Dec 2021 10:34:35 AEDT ]]>